With the end of Hugh Jackman's run as Wolverine coming to an end soon, it looks like Fox is ready to move on and reboot the whole X-Men franchise.
THR is reporting that Fox sees that "there are signs of wear and tear on ...[the] franchise" and that it is time to move on in a new direction. Apocalypse slightly underperformed and all of the major actor's contracts have finished up their three picture deals, meaning the studio would have to fork out a significant sum to bring them back.
Box office analyst Paul Degarabedian stated in the article that "you're gauged by the success of the franchise. This one [Apocalypse] didn't engender the love of previous movies. It's time to go back to the drawing board."
Add to that the end of Hugh Jackman as Wolverine and the production delay of a solo Gambit film with Channing Tatum, leaves Fox already planning on a Deadpool 3 that will introduce the X-Force. "Elsewhere, the reset button has been pressed. Sources say the flagship series will be reconfigured, with Simon Kinberg, overseer of the franchise as producer and writer, working on a new script. Singer, who directed four X-Men movies, will not be returning, according to insiders, but the script is being written with Lawrence, Fassbender and McAvoy optimistically in mind."